62 patients with lateral epicondylitis and associated radial tunnel syndrome were randomized to receive surgical treatment of lateral epicondylitis with either a radial nerve release/decompression or no radial nerve release/decompression. The primary outcomes of interest were the Quick Disability of the Arm, Shoulder and Hand (QuickDASH) score and the Mayo Elbow Performance Score (MEPS). Outcomes were measured at 1, 3 and 6 months post-operation. While both groups displayed improvements in QuickDASH scores and MEPS from baseline at all time points, there were no significant differences between the two groups in both outcomes measures at each post-operative period.