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Oral tranexamic acid is safe and effective in reducing post-operative blood loss in TKA
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Arthroplasty
Oral tranexamic acid is safe and effective in reducing post-operative blood loss in TKA
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Transfus Apher Sci. 2013 Dec;49(3):574-7. doi: 10.1016/j.transci.2013.09.005. Epub 2013 Oct 5

53 patients scheduled to undergo total knee arthroplasty (TKA) were randomized to either receive or not receive oral administration of tranexamic acid. The purpose was to determine whether this intervention was safe and effective in reducing the amount of postoperative blood loss. Results indicated that the tranexamic acid group displayed significantly better hematocrit levels post-operation and significantly lower bleeding rates 12 and 24 hours post-surgery. At 6 weeks postoperatively, there were no reported thrombotic complications in either group.

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OrthoEvidence. Oral tranexamic acid is safe and effective in reducing post-operative blood loss in TKA. ACE Report. 2014;4(4):36. Available from: https://myorthoevidence.com/AceReport/Report/oral-tranexamic-acid-is-safe-and-effective-in-reducing-post-operative-blood-loss-in-tka

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