Findings of two randomized controlled trials were pooled in order to investigate if method of corticosteroid injection - either image-guided or anatomical landmark guided (blind) - impacted clinical outcome in patients suffering from shoulder pain. Clinical outcomes of pain and function were reported at 6 weeks, and the incidences of adverse events were recorded. Pooled effects illustrated that pain and function at 6 weeks were significantly improved with image-guided injections compared to blind injections. Incidence of adverse events was also lower in image-guided group; however, the difference did not reach statistical significance.