Six randomized controlled trials (231 patients) were included in this analysis comparing short-term pain and functional outcome between a specific exercise program and general exercise program in the management of patients with subacromial impingement syndrome. Compiling data at 4-8 week follow-up, results demonstrated no significant differences between the two strategies in pain during activity, or in functional outcome. Further high-quality trials are needed to evaluate the efficacy of specific and general exercise therapies in this patient population, as there is currently insufficient evidence to support or refute the use of specific exercise strategies.