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Two Infusions of Zoledronic Acid Reduce Femoral BMD Loss after THA Measured over 2 years
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Arthroplasty
Two Infusions of Zoledronic Acid Reduce Femoral BMD Loss after THA Measured over 2 years
J Arthroplasty. 2013 Apr;28(4):671-5. doi: 10.1016/j.arth.2012.08.007. Epub 2012 Nov 8
Contributing Authors

DF Scott JN Woltz RR Smith

51 randomized patients were evaluated to compare the effects of two infusions of Zoledronic acid (ZOL) against a placebo treatment on bone loss density after primary cementless total hip arthroplasty. During the 2 year study period, radiographic data demonstrated that infusions of ZOL at 2 weeks and 1 year after surgery had substantially and safely suppressed bone loss density loss in seven Gruen zones, compared to a placebo. These differences were noted as early as 6 weeks.

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OrthoEvidence. Two Infusions of Zoledronic Acid Reduce Femoral BMD Loss after THA Measured over 2 years. ACE Report. 2013;3(6):20. Available from: https://myorthoevidence.com/AceReport/Report/two-infusions-of-zoledronic-acid-reduce-femoral-bmd-loss-after-tha-measured-over-2-years

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