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Pediatric Orthopaedics
Vitamin D supplementation for bone mineral density increase in osteogenesis imperfecta
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Pediatric Orthopaedics
Vitamin D supplementation for bone mineral density increase in osteogenesis imperfecta
Bone. 2016 May;86:36-42
Contributing Authors

L Plante LN Veilleux FH Glorieux H Weiler F Rauch

60 youth and adolescent patients with osteogenesis imperfecta (OI) were randomized to either high-dose vitamin D supplementation (2000IU daily) or low-dose vitamin D supplementation (400IU daily). The purpose of this study was to evaluate if high-dose supplementation led to a significant increase in areal bone mineral density (aBMD) z-score of the lumbar spine compared to low-dose supplementation over 1 year. Overall, there was no significant difference between groups in lumbar spine areal BMD z-score.

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OrthoEvidence. Vitamin D supplementation for bone mineral density increase in osteogenesis imperfecta. ACE Report. 2016;6(9):9. Available from: https://myorthoevidence.com/AceReport/Report/vitamin-d-supplementation-for-bone-mineral-density-increase-in-osteogenesis-imperfecta

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