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Previous Ace Report Region-specific and non-specific spinal manipulative therapy for chronic low back pain Next Ace Report Region-specific and non-specific spinal manipulative therapy for chronic low back pain
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Foot & Ankle
Zoledronic Acid increased hip BMD in acute Charcot neuroarthropathy
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Foot & Ankle
Zoledronic Acid increased hip BMD in acute Charcot neuroarthropathy
Foot Ankle Surg. 2013 Jun;19(2):121-4. doi: 10.1016/j.fas.2012.12.007. Epub 2013 Feb 20
Contributing Authors

H Maenpaa TK Pakarinen HJ Laine M Kahonen P Mattila J Lahtela

35 patients, suffering from acute midfoot Charcot neuropathy (CNA), were randomized to study the effects of zoledronic acid and immobilization on Bone Mineral Density (BMD) changes in lumbar spine and both hips. Patients were assigned to either receive zoledronic acid or a placebo treatment. 6 month results demonstrated a rise in hip BMD in zoledronic acid-treated group, and a fall in affected and non-affected CNA hip BMD in the placebo group. Immobilization and off-loading did not show signs of disuse osteoporosis.

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OrthoEvidence. Zoledronic Acid increased hip BMD in acute Charcot neuroarthropathy. ACE Report. 2013;3(9):11. Available from: https://myorthoevidence.com/AceReport/Report/zoledronic-acid-increased-hip-bmd-in-acute-charcot-neuroarthropathy

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