
Cannabis
Oral tetrahydrocannabinol (THC) does not reduce chronic abdominal pain compared to placebo
Clin Gastroenterol Hepatol. 2017 Jul;15(7):1079-1086.e4. doi: 10.1016/j.cgh.2016.09.14765 patients with chronic abdominal pain following surgery or due to chronic pancreatitis were randomized to receive delta-9-tetrahydrocannabinol (THC) or placebo for 50-52 days. The primary outcome was pain relief, as measured by a visual analogue scale (VAS). Secondary outcomes included other measures of pain, depression, anxiety, quality of life, treatment satisfaction, appetite, alertness, mood, calmness, safety, and tolerability. THC did not prove effective in reducing pain when compared to placebo in patients with chronic abdominal pain.
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