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General Orthopaedics
Hemoglobin based oxygen carrier-201: A safe and effective way to save packed blood
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General Orthopaedics
Hemoglobin based oxygen carrier-201: A safe and effective way to save packed blood
J Trauma. 2008 Jun;64(6):1484-97.
Contributing Authors

Jonathan S Jahr Colin Mackenzie L Bruce Pearce Arkadiy Pitman A Gerson Greenburg

688 patients, older 18 years, undergoing non-emergency orthopedic surgery were randomized to treatment with hemoglobin based oxygen carrier-201 (HBOC-201) or packed RBC at the first transfusion decision. After 6 weeks, HBOC-201 was found to be a suitable alternative to packed red blood cell transfusion for patients younger than 80 years with moderate clinical need, undergoing elective orthopedic surgery. A comparison of safety between the two treatment arms was unfavorable for the HBOC-201 patients, but this might have been affected by the patient age.

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OrthoEvidence. Hemoglobin based oxygen carrier-201: A safe and effective way to save packed blood. ACE Report. 2013;3(3):263. Available from: https://myorthoevidence.com/AceReport/Report/

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