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Previous Ace Report No advantage of patient-specific instrumentation over conventional instruments in UKA Next Ace Report No difference in 10-yr clinical outcome and survivorship between mobile- and fixed-bearing TKA
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Arthroplasty
Bone mineral density loss following total joint arthroplasty mitigated by bisphosphonate therapy
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Arthroplasty
Bone mineral density loss following total joint arthroplasty mitigated by bisphosphonate therapy
Osteoporos Int. 2018 Jul;29(7):1525-1537. doi: 10.1007/s00198-018-4488-7
Contributing Authors

Y Wang L Chen M Shi S Yan Z Xin W Wang

25 randomized controlled trials were included in this meta-analysis which compared bisphosphonate therapy to control intervention for effect on postoperative bone mineral density following total hip and total knee arthroplasty. Overall, in THA and TKA cohorts, bisphosphonate therapy was associated with significantly greater total periprosthetic bone mineral density compared to control intervention up to 5-10 year follow-up. Among THA cohorts, significant effects were located within Gruen zones 1, 2, 6, and 7.

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OrthoEvidence. Bone mineral density loss following total joint arthroplasty mitigated by bisphosphonate therapy. ACE Report. 2019;9(2):80. Available from: https://myorthoevidence.com/AceReport/Report/bone-mineral-density-loss-following-total-joint-arthroplasty-mitigated-by-bisphosphonate-therapy

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