82 patients with chronic mechanical neck pain were randomized to receive full manipulation, which included mid-cervical, cervico-thoracic and thoracic thrust manipulations, or to a group receiving cervical thrust manipulation alone. The purpose of this study was to determine if there was an added benefit of the full manipulation treatment to neck pain, disability and range of motion. After one week, both treatments demonstrated a similar improvement in pain and range of motion, although patient-perceived disability was more greatly reduced in patients who received the thrust manipulation to both the cervical and thoracic spine.